Description

Somatropin, or rh-GH, is a pure form of recombinant growth hormone produced by either mammalian or Escherichia coli bacteria. The pituitary produces endogenous human growth hormone (hGH). In 1956, the first growth hormone was extracted, and its structure was discovered in 1972. Growth hormone (GH) was previously generated from human cadavers prior to 1985; however, this practice was discontinued due to Creutzfeldt-Jakob virus contamination of the product. Somatropin is licensed for use in adults with short bowel syndrome, growth hormone deficit (GHD), growth failure, or short stature, as well as cachexia and AIDS wasting. In studies for the treatment of HIV-associated adipose redistribution syndrome (HARS), somatropin has been shown to reduce visceral adipose tissue, according to limited short-term evidence. There are numerous somatropin medications available, each with unique indications and dose guidelines. It is important to choose products carefully because they could not be interchangeable. The FDA initially authorized somatropin in 1987